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Lang GA, Iwakuma T, Suh YA, Liu G, Rao VA, Parant JM, Valentin-Vega YA, Terzian T,Caldwell LC, Strong LC, El-Naggar AK, Lozano G (2004) Gain of function of a p53 hot spotmutation in a mouse model of Li-Fraumeni syndrome. Bydefinition, free radicals possess an unpaired electron withintheir chemical structure, which makes them highly reactiveand therefore capable of damaging intracellular molecules,including lipids, proteins, and nucleic acids.
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